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Genta Reiterates Company Progress And Timelines For Genasense<sup>TM</sup>

October 8, 2002
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BERKELEY HEIGHTS, NJ October 8, 2002 - Genta Incorporated (Nasdaq: GNTA) presented an overview of the companies pipeline, programs and strategic initiatives for future growth yesterday at the UBS Warburg Life Sciences conference in New York. The presentation included an update on the continued progress of Genta's lead anticancer compound, Genasense TM , along with a comprehensive overview of the current clinical trials programs. The Company currently has three randomized clinical trials that employ Genasense TM  plus chemotherapy in patients with malignant melanoma, multiple myeloma, and chronic lymphocytic leukemia. Enrollment into these trials remains on track, consistent with previous guidance. The Company also reiterates its confidence that a positive result from any one of these trials will enable the Company to file a New Drug Application (NDA) on schedule by the summer of 2003, consistent with previous guidance. Genasense TM  has received Orphan Drug designation by the Food and Drug Administration (FDA) for each of these three indications. The Company has also received Fast Track designation for melanoma and myeloma. For a review of the archived audio webcast this presentation please visit: http://www.ubswarburg.com/e/homelinks/conferences/index.html . The audio will be available for 30 days.

About Genasense TM  

Genasense TM  works by inhibiting the production of Bcl-2, a protein made by cancer cells that is thought to block chemotherapy-induced cell death. By reducing the amount of Bcl-2 in cancer cells, Genasense TM  may enhance the effectiveness of current anticancer treatments. Genasense TM  is currently in multiple late-stage randomized clinical trials including malignant melanoma, multiple myeloma, chronic lymphocytic leukemia (CLL) and non-small cell lung cancer. Genta is also conducting additional clinical trials in leukemia, lymphoma, and cancers of the lung, breast, and prostate.


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