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Genta Announces Licensing Deal For Antisense Technology To Oasis Biosciences

September 28, 2000
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BERKELEY HEIGHTS, NJ, September 28, 2000 - Genta Incorporated (Nasdaq: GNTA ) today announced completion of its second out-licensing agreement for antisense patents to Oasis Biosciences, Inc., San Diego, CA. The non-exclusive license agreement includes upfront payments in cash and royalties on product sales. Fundamental claims in this patent portfolio involve methods, compositions, and processes for in vitro and in vivo inhibition of protein synthesis by antisense oligonucleotides. Issued claims in the portfolio are exceptionally broad and enabling for most pharmaceutical uses, as well as many diagnostic applications. Genta retains rights to the patents for its own use, as well as an exclusive right to grant unrestricted sublicenses to other users.

"This license represents the second transaction of this type for Genta. We expect to notify other companies who we believe will benefit from obtaining a similar license. This strategy will both accelerate the adoption of antisense technology for clinical uses, as well as enable Genta to share in profits related to these new ventures," said Mr. Thomas Burger, Vice President, Corporate Development. "The early priority date and exceptionally broad claims in these patents will be used to aggressively extend our position in this field."

Jurgen Schrenk, President and CEO of Oasis Biopharmaceuticals commented: "We feel the license to these patents is essential to practice Oasis"s proprietary technology for high - throughput target validation, and will also allow us to commercialize its results for the research market as appropriate. We are pleased with the rapid completion of our negotiations and look forward to the continuation of our mutually rewarding collaboration with Genta."


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